Omtrent 7-9 % af den kaukasiske befolkning har variationer i CYP2D6 genet som koder for ingen- eller nedsat aktivitet af CYP2D6 (se personlig medicin ). Tramadol et produg der omdannes til den aktive metabolit by way of CYP2D6. Patienter med nedsat eller manglende aktivitet af CYP2D6, vil have reduceret- eller manglende effekt af tramadol.This anal
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Don't just the conservative previous Minister of Justice along with the existing Social Welfare Metropolis Commissioner of Stockholm are advocating this by way of example, but also Associates from other functions likewise. A reaction to criticism on the proposal would be that the well being of the youngsters is more essential than their integrity."
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